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Cellular Nutrient Synergy in Health: This is because the nitrogen to phosphorus N: Arbuscular mycorrhizal fungi contribute to phosphorus uptake by wheat grown in a phosphorus-fixing soil even in the absence of positive growth responses. Having said this, what stack would you recommend me to start with to gain value from nootropics? Dee, Mucuna Pruriens https:

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Meal frequency and timing in health and disease

Dietary folate and VB12 were also suggested to be protective factors for coronary heart disease. Texas Heart Institute Journal ; 34 3: Because adrenergic beta antagonists are not sufficient to prevent atrial fibrillation after coronary artery bypass grafting, this prospective, randomized trial was designed to evaluate the effects of ascorbic acid as an adjunct to beta-blockers.

Fifty patients formed the ascorbic acid group, and another 50 patients formed the control group. All patients were older than 50 years, were scheduled to undergo coronary artery bypass grafting, and had been treated with beta-blockers for at least 1 week before surgery. The mean age of the population was Patients in the ascorbic acid group received 2 g of ascorbic acid on the night before the surgery and 1 g twice daily for 5 days after surgery.

Patients in the control group received no ascorbic acid. Patients in both groups continued to receive beta-blockers after surgery. Telemetry monitoring was performed in the intensive care unit, and Holter monitoring was performed for 4 days thereafter.

The study concludes that ascorbic acid is effective, in addition to being well-tolerated and relatively safe. Therefore, it can be prescribed as an adjunct to beta-blockers for the prophylaxis of post-bypass atrial fibrillation. This confirms earlier findings of the double-blind placebo controlled study conducted by the Dr Rath Research Institute.

This clinical study demonstrated that a specific synergy of micronutrients used as an adjunct to conventional treatment provides significant improvements in decreasing frequency, severity and improving life quality of arrhythmia patients. Journal of Clinical Hypertension ; 9 4: Active treatment increased brachial artery diameter by 2. Thus, mitochondrial dysfunction may contribute to the regulation of blood pressure and vascular tone.

The Journal of Nutrition ; 2: Certain nutrients have been shown to be effective in preventing coronary heart disease. This study hypothesized that a daily intake of low amounts of a number of these nutrients would exert beneficial effects on risk factors and clinical variables in patients that suffered from myocardial infarction MI and were following a cardiac rehabilitation program.

Forty male MI patients were randomly allocated into 2 groups. The study shows that plasma concentrations of eicosapentaenoic acid, docosahexaenoic acid, oleic acid, folic acid, vitamin B-6, and vitamin E increased after supplementation P http: The Journal of Nutrition ; 6: Consumption of tree nuts such as almonds has been associated with a reduced risk of coronary heart disease.

Flavonoids, found predominantly in the skin of almonds, may contribute to their putative health benefit, but their bioactivity and bioavailability have not previously been studied. The aim was to investigate the effect of Ubiquinol supplementation on physical performance measured as maximum power output in young and healthy elite trained athletes.

In this double-blind, placebo-controlled study, young German well trained athletes received either mg Ubiquinol or placebo for 6 weeks. In these 6 weeks all athletes trained individually in preparation for the Olympic Games in London Both groups, placebo and Ubiquinol, significantly increased their physical performance measured as maximum power output over the treatment period from T1 to T3.

While adherence to a training regimen itself resulted in an improvement in peak power output, as observed by improvement in placebo, the effect of Ubiquinol supplementation significantly enhanced peak power production in comparison to placebo. Professional football players may experience negative health consequences when they retire such as chronic pain, cognitive problems as well as other consequences of sports-related injuries.

The purpose of this pilot study is to determine the effects of dietary supplementation with multiple nutrients on the quality of life of retired football players. Fifteen retired players received daily supplementation of fish oil with cholecalciferol, antioxidants, natural vitamins and minerals, polysaccharides and phytosterol-amino acid complex for 6 months. Using an open-labeled repeated measures design, volunteers completed self-report assessment measures at baseline, 1, 3 and 6 months.

Mental health days improved at 6 months. Vigor scale in POMS was significant at 3 months. Decreased pain was noted only for the elbow at month 1 and the knee at month 3. No adverse events were reported. Results of this study offer preliminary insight into using dietary supplements to support and optimize quality of life in retired football players. Further research using a placebo-controlled design is needed to characterize the potential benefit to physical and psychological well-being of multiple dietary supplementations for this cohort.

Bioscience, Biotechnology, Biochemistry ; 73 2: The effects of an orally administered combination of a glucosamine-chondroitin-quercetin glucoside GCQG supplement on the synovial fluid properties of patients with osteoarthritis OA and rheumatoid arthritis RA were investigated from the clinical nutrition view point.

Several parameters of the knee joints were monitored before and after supplementation. The OA patients showed a significant improvement in pain symptoms, daily activities walking and climbing up and down stairs , and visual analogue scale, and changes in the synovial fluid properties with respect to the protein concentration, molecular size of hyaluronic acid, and chondroitin 6-sulphate concentration were also observed.

However, no such effects were observed in the RA patients. These results suggest that the GCQG supplement exerted a special effect on improving the synovial fluid properties in OA patients. Glucosamine sulfate and chondroitin sulfate have been evaluated in many studies as agents to relieve pain, improve functional activity, and slow disease progression in OA especially of the hip and knee. Primorine is a combination of products thought to alter these biochemical oxidative byproducts.

Based on current evidence, the use of a combination product of glucosamine sulfate and chondroitin sulfate seems to have the greatest potential as a therapeutic intervention for patients at increased risk from the adverse events of accepted current oral therapies. The use of primorine and its combination of products as an intervention in OA has theoretical advantages but its benefits are unproven.

A new product, relamine, is a combination of these three formulations. While no studies have evaluated glucosamine sulfate, chondroitin sulfate and primorine in a single product, it may be an option for those who wish to try an alternate therapy for OA, as there appears to be a low risk for serious adverse events.

European Journal of Clinical Nutrition ; 63 4: The objective of this study was to assess the effectiveness of a multivitamin MV tablet on nutritional status, quantitative heel ultrasound QUS , mobility, muscle strength and falls.

The design comprised two groups matched on mobility levels, randomized to receive a daily MV or placebo P tablet for 6 months. A total of 92 aged care residents participated in the study. The setting was an Australian residential care facility. Serum micronutrients, body weight, QUS, rate of falls, hand grip strength, and the timed up and go test were assessed at baseline and 6 months.

A total of 49 participants consumed a MV and 43, a matched P for 6 months. The study concludes that MV supplementation raised serum vitamin B12 and folate concentrations and increased serum 25 OH D, which was accompanied by an apparent positive effect on bone density.

The study also found a trend towards a reduction in falls and this could contribute to a reduction in fractures.

A mildly elevated homocysteine Hcy level is a novel and potentially modifiable risk factor for age-related osteoporotic fractures. Elevated Hcy levels can have a nutritional cause, such as inadequate intake of folate, riboflavin, pyridoxine or cobalamin, which serve as cofactors or substrates for the enzymes involved in the Hcy metabolism. This study examined the association between intake of Hcy-related B vitamin riboflavin, pyridoxine, folate and cobalamin and femoral neck bone mineral density BMD FN-BMD and the risk of fracture in a large population-based cohort of elderly Caucasians.

The study involved individuals aged 55 years and over from the Rotterdam Study. Dietary intake of nutrients was obtained from food frequency questionnaires. The study concludes that increased dietary riboflavin and pyridoxine intake was associated with higher FN-BMD. Furthermore, the study found a reduction in risk of fracture in relation to dietary pyridoxine intake was independent of BMD. These findings highlight the importance of considering nutritional factors in epidemiological studies of osteoporosis and fractures.

Cancer Prevention Research ; 2 5: The previous study showed that administration of a combination of micronutrients selenium, vitamin E, and lycopene inhibits prostate cancer PCa development in the Lady transgenic model. The present study has examined timing of initiation of micronutrients, and the effect of micronutrient combinations, on PCa development in Lady transgenic model. Breast Cancer Research and Treatment ; 3: Have you researched any of the nootropics for this unfortunate illness?

If you have can you help me out? I use L-Tyrosine perhaps is not enough. Let me know if this is a good balance. The Cleveland Clinic says you can dose L-Theanine up to 1, mg per day. Huperzine-A may be a good choice but please carefully read the dosage notes about cycling this nootropic.

And while Vinpocetine is currently easier to get than Picamilon here in the USA not sure about Canada , Picamilon may be a better option for your situation. For L-Tyrosine, you can dose up to 2 grams per day. Then click through to the review on each nootropic on that page. I am learning so much from your site. Except I am still not sure what would be best to take for an interview. I also have autoimmune and it cause lots of brain fog and fatigue, which gets worse during interviews.

I need something to relax me, but not make me sleepy! Something for verbal fluency and quick thinking, focus, and alertness would be awesome! I have been trying Ashwagandha for a few days, but not sure if I feel right on it. Especially the part about its effect on the immune system and thyroid. This may not be the nootropic for you.

Particularly the side effects and dosage recommendations. Other suggestions are Aniracetam, magnesium, Rhodiola Rosea, and a high quality B-Vitamin complex that includes folate not folic acid and B12 — methylcobalamin not cobalamin. I noticed you have hypothyroid. I have autoimmune hashimotos, which results in hypothyroid. Curious what you take for that.. Also one of the reasons I started Nootropics Expert.

Because being hypothyroid took my brain offline. Nootropics turned my life around degrees. Dosed throughout the day. My doc put me on Alpha Lipoic Acid for insulin resistance a couple of months ago. And that messes with my thyroid meds. It took me about 3 months to find out that Synthroid was making me sicker. It took another 3 years to get my body back into good enough shape using natural desiccated thyroid to start thinking about fixing my brain.

I just received my Phenibut and LTheanine. I plan on trying Phenibut tomorrow as a test without taking anything else. I plan on using L-Theanine on a regular basis with my daily supplements. I get it with the Thyroid question…it was more out of curiosity. I refused all Thyroid Meds from the Doc.. My TSH is under 4, so trying to get it down between I will keep trying different things till it happens!

You can send your blood test results to life extension magazine ànd put on the envelope lab review and one of their specialists will go over your blood work with you. I got to talk with a naturopath Dr one to e for over an hour a e they love to help people.

In searching the internet for information on Nootropics, your website really stands out. Do you know of one that will help with these problems? I have this problem along with my 10 year old Son. Disrupting that natural development is a dangerous thing to do. So proceed with caution with any nootropics. And finally, you may want to consider Mind Lab Pro. So please search NootropicsExpert. Hi David,honestly this is extremely comprehensive website that i have seen.

Is there any supplement that can help? Kaveh, racing thoughts could be caused by an imbalance of glutamine and glutamate in your brain. So my first suggestion is to try supplementing with L-Glutamine to see if that helps.

Please read the reviews on each of these here on Nootropics Expert. Picamilon will be up in the next couple of weeks. This is a great site, and filled with valuable information.

Thanks for all the fantastic advice and in depth articles. As a nootropic newbie, looking to try to get more focus and motivation in life generally I do not sleep well and my mind is all over the place, might even be ADHD I was looking for a nootropic to assist.

I started with this and did see some slight increase in focus, but my mind was still all over the place. The FLModafinil did cause some nausea but nothing unbearable. However, I did get an urge to sleep after a few hours and sometimes immediately after taking it especially if I was notworking or doing anything.

Having said this, what stack would you recommend me to start with to gain value from nootropics? I am just very confused with the vast amount of nootropics on the market. I am happy to start small. Ash, great questions and I have a couple of suggestions. Your reaction to FL Modafinil is interesting. One of the neurotransmitters it affects is histamine which you could have a problem with.

But it would take much more research on your part to learn exactly how FL Modafinil works in your brain. According to the labels on Neuroactive Day and Neuroactive Night, the doses in some of the ingredients are much below therapeutic doses to provide much benefit. And why you get only some benefit from using them. I suggest you take a close look at my favorite pre-made stack called Mind Lab Pro. And thousands of other neurohackers as well. And they do ship to South Africa.

Dear David, Along with each mg of berberine, how many mg. Sincerely, Phill Phoenix, Arizona. Phill, one study found that mg of Silymarin with 1, mg of Berberine was most effective.

Silymarin is one of the active compounds in Milk Thistle. Thanks so much for the in depth response. I am still in awe of how you personally respond to each message you receive. For now mind lab pro is a little pricey for me. Having read a few of your articles, and others online I am considering moving to racetams. I have heard good things about Noopept and Aniracetam. I think the Alpha GPC is to absorb the racetams?! Theanine and caffeine probably test it seperately and Lions Mane for the repair function.

I was basically reading articles on this website and others and adding what was available to my cart. No idea how much of each to take at 1st, or how to combine if I should. Can you maybe provide some of your advice on what will be good to start with and what not based on the above? Also, probably would prefer starting and testing individually before stacking. Ash, you can use everything you currently have on your list as long as you follow the dosage instructions closely.

Dosage instructions are explained in detail on each review page here on Nootropics Expert. Always start with the lowest recommended dose and see how your body reacts. Aniracetam and Noopept both affect acetylcholine use in your brain. So you must provide your brain with a precursor to make sufficient acetylcholine for these nootropics to work effectively. Caffeine should be taken with L-Theanine to prevent the jitters that often come with caffeine use.

Again, this is explained in detail in the L-Theanine review. One more thing about dosing: But always start with the lowest therapeutic dose to see how you react! I appreciate your compliments on Nootropics Expert.

Dear David, great website and a wealth of good knowledge. I was wondering I have just started taking mind lab pro; which I have read a great deal about along with great reviews.

I take ciprilex antidepressents for many years. I still feel very flat sometimes.. I eat healthy and walk a lot. Oliver, depending on the person, it may take anywhere from 1 — 3 weeks to experience the full effects provided by Mind Lab Pro. But this SSRI very much complicates correcting the motivation issues you mention. Cipralex prevents the reuptake of serotonin in your brain.

And has an effect on at least one of the serotonin transporters. Meaning you have more serotonin available. Because the synthesis of both serotonin and dopamine depend on the same enzyme. I think everyone should be supplementing with iodine and selenium to support thyroid health. Given your age and you are male, you may want to get a full testosterone panel done including estradiol.

Also a full thyroid panel and learn how to read your own lab results. I know because it took me almost 5 years. But it was worth the journey. Nootropics saved my life and things are better now than ever for me. So please continue your research and do not be afraid to cautiously experiment.

Can you give me some peer-reviewed medical journal websites that you use to get some of your information? Do you use pubmed? Also, what are your thoughts about probiotic use? Good luck with your psychiatrist. The pharmaceuticals dictate what is taught to young doctors. And of course are only exposed to pharmaceuticals to treat disease. Most doctors are much too busy or simply do not have any interest in thinking outside the box.

But I do not want to go down the political, moral or ethical road with Nootropics Expert. I was reading through this website and wanted to try some supplements but not sure if it works well with the concerta.

I live in Finland so getting mind lab pro is not possible so as to any of the racetam family. Currently, i am taking zink 15mg , magnesium mg and omega 3 with very high epa ratio to dha.

Zabe, you are on the right track with what you are currently doing with your stack. Look through the ingredients list in Mind Lab Pro for ideas on how to make your stack better. For example, get a nootropic supplement that increases cerebral blood flow. Something like Vinpocetine or Pine Bark Extract.

Add a high quality, bio-available B-Complex formula to your stack because you need the B-Vitamins to synthesize neurotransmitters. And you should also consider adding a tablespoon of high quality fat to your stack. Preferably cold-pressed, unrefined coconut oil or olive oil. You need this fat to help deliver some of the fat-soluble nootropics you are using. Check the review on each here on Nootropics Expert to learn which are fat-soluble.

Thank you a lot a David. I will definitely buy the DHA mg and the high quality fat Also high standards bit B and the other supplements you suggested. I make my own capsule for several nootropics I use. As for racetams, what are you trying to achieve? The most popular racetams are Aniracetam, Piracetam, Oxiracetam, and Phenylpiracetam. But each have their own characteristics and benefit that each provides. He struggles with anxiety and mild depression as well as social anxiety. I have him talking the Calm Now blend off Amazon as well as a raw organic multi B vitamin blend and ashwaganda.

For my husband, he struggles with mild ADD — undiagnosed, but he has a short attention span and has headaches. Third is my friend — she was diagnosed with bipolar and ADD. She takes pharmaceuticals, but would like to get away from them. For myself, I am 39, and I use to have a very sharp mind.

From the extreme stress of the last 2 years fighting in court over my children and other things — my memory is now just awful. I most likely have some PTSD and extreme stress etc. I have tried a few Neuro blends. My short term memory is awful and I have trouble with recall of my long term memories also. I can focus alright. My main issue is memory. But it will take some trial and error and a lot of patience.

Because each of us is different. Including your son, husband, friend and you. But a strong word of caution. Each of the nootropic stacks suggested has links through to full reviews for each of those supplements. Some of these can be extremely dangerous. And you must heed the warnings.

Because very bad things can happen. It took me several years before I finally found that sweet spot where I felt good again. In fact, better than I have in a long, long time. But it took a lot of experimenting. David, Terrific website and information. Your insight and research are inspiring and appreciated. Have you checked out the post I wrote on nootropics and ADD? You may get some ideas on how to support what you are currently using.

And get better results. If you would like, I will compile and type one for you. Where is that, please? Helen, nootropics literally saved my life not too long ago.

Nootropics Expert is my way of giving back and hopefully help someone else turn their life around. This site is a constant work in progress and I have some web-design geniuses working on a site update for early An index of some kind may be the answer. For now however, to search the hundreds of pages here on NootropicsExpert. Is that price justified? Altho I am complaining gingerly because my mood is definitely on the upswing. NTL, do you really think it would be more expensive to buy the ingredients separately?

Helen, Mind Lab Pro is a day supply and not Unless of course you get the discounted 3-month supply. From your experience, Should I take them at the same time or would they work better taken separately through out the day? Mike, those 4 nootropics all support each other so there is no harm in taking them together. And for all the nootropics you are going to try please follow the dosage recommendations closely for best results. I really am grateful for the immense amount of effort that you gone to in organizing all of the information in one place.

I have been studying it for a couple of weeks with great relish. I am a 71 year old man who has been interested in these areas of supplementation for the last 20 years. I have recently been looking for more information on pregnenolone without too much success and was wondering if you have explored this substance. I am also wondering if you have a recommend stack with spiritual clarity and focus as a goal?

I personally use progesterone on the advice of my doctor. But it may now go on my list. My story begins with a mercury toxicity test result of Ended up with acute pain and perscribed high dose opiates for a decade. Currently off Fentanyl 15 weeks, replaced by monthly buphronephrine injections, as part of a clinical trial. Is working wonders, no pain. However, the past 3 years my cognitive dysfunction has declined to the point of losing my business, my home, am in financial ruin.

That this will cure me of my cognitive issues! I KNOW being in acute pain again will not help at all. They will not perscribe Ritalin — a mental health care facility, what a joke! Debbie, it is difficult for me to recommend any particular doctor who specializes in ADD. I was fortunate that once I was diagnosed 10 years ago and started on Ritalin I was able to switch docs as needed.

Try subscribing to this mag and see if you can get someone to point you in the right direction: Without a doubt I know it was using Mind Lab Pro as my base and building from there I was able to pull that off. I avoid antidepressants like the plague.

They will absolutely make your situation worse. While I believe prescription antidepressants may have their place for a fortunate few, most will have better luck using the right nootropic supplements. Please get your thyroid levels checked out too. This area of healthcare needs to be managed by you because I have not yet met an endocrinologist who gets it.

Spend some time reading https: Then find a naturopath or functional medicine doc who will work with to order the right labs. But use the thyroid site to learn how to read the labs yourself. It sounds like you are on the right track. It took me 3 solid years of experimenting and healing before I was functional again. The first couple of chapters will encourage you to continue what you are doing. And the rest of the book will help you focus on each of the issues you are dealing with.

Thank you so much for this invaluable site. I started with nootropics a year ago with Neuro1 which I acquired a large volume of from a liquidator for next to nothing. My supply has run out, and rather than pay the price premium for that product, I decided to get serious about my nootropics and roll my own.

Prior to workouts, I also add the following: Most of this stuff was bulk powder rather than capsules, and to get it down I heat 1Tbs of extra virgin coconut oil in the microwave till it liquifies, then mix in the powder and down the shot.

I had planned to add R-ALA, but the batch I received had polymerized into a plasticy mess, and I opted not to put it into my body. Try using Vinpocetine 2 or 3-times per day. Increase DHA to 1, mg. Increase Vitamin D3 to a least 2, IU. NADH, zinc and copper are good idea. But use 2 mg of copper. And not sure why you would want to go with Unifiram.

There are at least 6 other racetams with a lot more human clinical studies backing up their use. BTW, I should also probably mention that I have a hypoactive thyroid and take mcg of levothyroxine every morning, in case that has any bearing on the matter. Has your experience been different? My body will not convert synthetic T4 to T3 and the other bits my body can use.

You must be one of the lucky ones where levothyroxine works for you. You likely should be using iodine and selenium as well as they are required to synthesize your thyroid hormones. BTW, being hypo absolutely affects nearly everything in your body. Jalene, I do not have an opinion on Qualia yet. But will be doing a review of their stack sometime later this year. For the initial dosage I believe you said to mg per day. Is that mg of l-dopa as a percentage from the Mucuna supplement?

That is what we are basing our dosage on. Would cycling this lower amt of L-dopa be prudent? If yes what type of cycling protocol would you recommend? But if you are experiencing the benefit of L-DOPA at that dose … then to get the full experience I recommend using it for 5 days and taking 2 days off.

HI David, I am enjoying your videos. Hope I am posting in the right spot. I began taking Modnifil which really worked for me. I am a shift worker who frequently crosses over from nights to day visa versa.

I added in arcalion Subutiamine and Hunasun Citcholine mg. I then decided to buy the mind lab pro stack pack. It arrived in Asia yesterday. Would you recommend I drop some or all of what I have been taking and just see where the mind lab pro stack takes me? I am noticing great retruns in focus and drive so far. I had a near drowning a couple of years ago and yes some parts of the brain have slowed a little, that much is clear LOL.

Any advice greatly apprecited. But each of us is wired differently. So your response may be different. Try it and see how you feel. Hello David, I just came across your video about L-Theanine. I am taking Xanax at. Should I watch out for anything funny?

I have problems with anxiety. It also increases dopamine. Combining the two could cause problems with excess GABA and dopamine. Whenever you start mixing pharmaceuticals with nootropics you are playing with fire.

But common sense tells us that too much of any one neurotransmitter throws everything out of balance. And at times, can be deadly. But if you do be extremely careful. And listen to your body. Hello David, Thank you again for all of your help. Do you think I might have done any damage, long term or otherwise…to myself by mixing the Xanax with L-Theanine, and how would i know?

Sorry about the other posts below, I see how you comment and reply system works now. Without your video…and this web-site, I might have continued on mixing the Xanax with L-Theanine, but will not do that again. All the best, John. John, short of getting a deep brain scan there is no way to tell if this combo caused any damage. The human brain has an amazing ability to repair itself. But I think stressing about it will cause more damage than anything else.

Any thoughts as to why Xanax is a bad mix with L-Theanine, I am guessing that it might slow down a persons breathing…. David, thank you — I missed your reply when I sent the second message. I did not fully understand what I was getting into.

I also did not understand that they worked in a similar manner. How long do you think I should be off the xanax. John, the half-life of Xanax is around 11 hours. The half-life of L-Theanine according to the following study ranged from 58 min to 74 min in humans. Below is a brief summary of my medicated world of mental health:. Which explained a lot of my academic struggles, feelings of self-worth, etc. She started out by prescribing me a Sustained Release generic version of Wellbutrin.

I am both a teacher and a student… She had also prescribed some sort of non-addictive anti-anxiety medication which made me feel ill so I discontinued use within just a few days. I try to eat healthfully, and I try to practice self-care as much as possible. That, and a new hormonal birth control, has really thrown my life off kilter.

At first, Adderall helped with getting all my work done! Staying focused, on-task, memory, etc. But more recently, I have experienced increased irritability and strong fits of anger… paired with a seemingly greater tolerance to Adderall? It seems to last for a shorter time. I have been trying to track how these emotional reactions relate to the time of the month, but is increasingly difficult to track the timing of my mood swings. My partner has also noticed a change in my behavior.

I try to take breaks from Adderall, but I find it quite difficult with an increased workload as of late. Research into Nootropics, though, gives me hope that there is a better solution for my struggles. What would you recommend? I would like to taper off of prescription drugs, ideally. Perhaps come summer time, when I experience a true break, I will be able to relax more with a decreased work schedule….

Vitamin B-complex, L-theanine, L-tyrosine, Magnesium. Perhaps a cycled 5HTP? Thank you in advance for your consideration. Michelle, sounds like Adderall is providing too much norepinephrine which is what could be the source of irritability. You may do better with IR Ritalin. But the few months I experimented with Adderall resulted in symptoms like you describe.

So it was back to Ritalin. I seem to remember more than one nootropic supplement that could help tame PMS symptoms. I have the latter. I titrated off the Mirapex because the dose was too high and I was on the verge of psychosis.

I was unable to sleep or eat. However, at the least amount of dosage, I was finally able to fall asleep. My neurologist wants to put me back on the lowest dosage again. Could you suggest a stack that might help? I also have Generalized Anxiety Disorder and Adult ADHD along with migraines with aura and occasional hemiplegic migraines, chronic long term back pain from a spondylolisthesis, and osteoarthritis throughout.

I figure the more details I give, the better you might be able to analyze my situation. Dee, Mucuna Pruriens https: Keep an eye out specifically for dopamine antagonists. I recall at least one or two nootropics for migraines. Robert, Galantamine is sold as a prescription drug in the United States and elsewhere. Here on Nootropics Expert we stay primarily with natural substances that can be used for brain health.

And some of the racetams that can easily and affordably found on nootropic vendors websites. So Galantamine will not likely be going on my list to review any time soon. Hello, I have just watched your video regarding lithium orotate. I have a 21 yr old with severe autism, hyperactivity disorder, anxiety disorder, OCD, epilepsy with extremely challenging behaviour. He currently takes mg twice a day carbamazepine, 10mg fluoxetine plus 60mg of propranolol daily.

Would 5mg of lithium orotate daily be safe with these meds? Sharon, I highly recommend you learn as much as you can about each of the drugs you mention here. Get a clear understanding of their mechanism of action especially in the brain. Then check each one for interactions here: Keep in mind that when lithium is mentioned on drugs.

And used in very high doses. I cannot give you a definitive answer either way because the drugs being used here are extremely potent. And mixing them with any nootropic supplement could be a recipe for disaster. So be very, very careful. Hi i have just received my first nootropic samples today which consisted of, 15caps aniracetam mg , 15caps oxiracetam mg , 15caps piracetam mg ,15caps noopept 30mg , 60caps alpha gpc mg and a bottle of phenibut hcl mg.

I took 1 aniracetam and 1 aplha gpc today and the feelings was absolutely unreal i felt the best i had in years im 26 years old although i felt a bit sleepy and possibly slight brain fog rather than enhanced cognition, my question is what is the best way to take these, should i stack them to get maximum benefits or take them all consecutively?

Alan, we have detailed dosage instructions for every one of these nootropics. Scroll through the list here: And click through to each review. Each review explains how the nootropic works in your brain. The amount to use and what to take with it to make sure it works. I also suggest you only use one racetam at a time until you learn how each works.

And how your body responds to it. You likely felt sleepy because your dose of Alpha GPC was too low for the amount of Aniracetam you took. If you miss either of those it is unlikely you will experience much from using this nootropic. And it then feels like nothing is happening. Driving north early in the morning on I was amazing. Everything was crystal clear and my reaction time moved up a couple notches. But when I miss using Aniracetam for 3 or 4 days in a row I know it.

Would it be safe for me to start taking nootropics at this age? Somewhere on this site is research on brain development and age. But it would take some searching to find it.

And if you did, be very careful about what you use. But most of the serious heavy lifting is from birth to late teens. So in your case and at your stage of develop just please be careful.

That includes stuff you can get off the interweb. The racetams should be OK as long as you follow dosage instructions very carefully. And no matter what you do support your brain with the basics. That with unrefined coconut or MCT Oil can give you an edge. Final word is use common sense. You can up your game without over-amping your brain. Always do the fundamentals no matter what you try. And use adaptogens and anything that assists nerve growth factor and BDNF. Continual brain repair and listening to your body is key.

David thank you so much for the quick reply! Charles, best way to get a better understanding of nootropics and different options for stacks is read some of the posts linked to from this page: Each post title is fairly descriptive of what the post is about.

And there is a short summary there as well. I also just ordered Mind lab pro! Also, would it be worthwhile to add ashwagandha to the stack? Mostly as another adaptogen and the reaction timing and calmness its known for? And adding one regular dose of Mind Lab Pro will increase it to 1, mg total. Ashwagandha is an acetylcholinesterase inhibitor. Which means it increases acetylcholine ACh. Adding it to your stack will push you over the top into nasty territory more than likely.

With too much acetylcholine. Mind Lab Pro benefits kick in at different times for different people. But may not notice a difference for awhile. The effects are powerful but subtle because it works on total brain optimization. And unless you are very in-tune with your body …. I would start with one dose of MLP and see how you feel.

I personally use one dose of MLP in the morning and another at noon. But my brain is very Adult ADD. And needs the help. Piracetam may give you the noticeable difference you are looking for. But please follow dosage instructions carefully. And take another look at the amount of Citicoline you are using. And carefully evaluate each one before adding any one of them to your stack.

How much citicoline would you recommend then?

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