Human digestive system

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Digestive System of the Upper Torso
It is always associated with antecedent events such as premonition, nausea, salivation, or shivering and is accompanied by repeated contractions of the abdominal muscles. Various pathogens can cause gastroenteritis an inflammation of the stomach and small intestine. Although inguinal hernias are common in young foals, they rarely cause clinical problems; the situation is considerably different in stallions. Intestinal obstruction happens once there's a blockage of your tiny or gut. The rate can be modulated by the rest of the autonomic nervous system.

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ICD-10 Version:2016

The submucosa , just external to the mucosa, is areolar connective tissue containing a rich supply of blood and lymphatic vessels, lymphoid follicles, and nerve fibers which supply the surrounding tissues of the GI tract wall.

Its elastic fibers enable the stomach to regain its normal shape after temporarily storing a large meal. Th muscularis externa, also called the muscularis surrounds the submucosa. The muscularis is responsible for segmentation and peristalsis.

It typically has an inner circular layer and an outer longitudal layer of smooth muscle cells. In several places along the tract, the circular layer thickens and forms sphincters that act as valves that control food passage from one organ to the next, they also prevent backflow.

In most alimentary canal organs, its made up of areolar connective tissue covered with mesothelium , a single layer of squamous epithelial cells. In the esophagus, which is located in the thoracic instead of the abdominopelvic cavity, the serosa is replaced by an adventitia , ordinary fibrous connective tissue that binds the esophagus to surrounding structures. Retroperitoneal organs have both a serosa facing the peritoneal cavity and an adventia on the side abutting the dorsal body wall.

Your email address will not be published. If you study biology or medicine, having a solid understanding of homeostasis is extremely important. All living systems are based. One of the basic concepts in anatomy and physiology is the idea of organization. Levels of structural organization in the. The heart is an extremely interesting and powerful pump. It operates by using an intrinsic control and conduction system that.

Did you know the digestive system is split into two main groups? Did you know one of the groups is. Histology of the Alimentary Canal Digestive System: Histology of the Alimentary Canal January 9, 0 Comments. The mucosae are highly specialized in each organ of the gastrointestinal tract to deal with the different conditions.

The most variation is seen in the epithelium. The submucosa consists of a dense irregular layer of connective tissue with large blood vessels, lymphatics, and nerves branching into the mucosa and muscularis externa. It contains the submucosal plexus , an enteric nervous plexus , situated on the inner surface of the muscularis externa.

The muscular layer consists of an inner circular layer and a longitudinal outer layer. The circular layer prevents food from traveling backward and the longitudinal layer shortens the tract. The layers are not truly longitudinal or circular, rather the layers of muscle are helical with different pitches.

The inner circular is helical with a steep pitch and the outer longitudinal is helical with a much shallower pitch.

Whilst the muscularis externa is similar throughout the entire gastrointestinal tract, an exception is the stomach which has an additional inner oblique muscular layer to aid with grinding and mixing of food. The muscularis externa of the stomach is composed of the inner oblique layer, middle circular layer and outer longitudinal layer. Between the circular and longitudinal muscle layers is the myenteric plexus. Activity is initiated by the pacemaker cells, myenteric interstitial cells of Cajal.

The gut has intrinsic peristaltic activity basal electrical rhythm due to its self-contained enteric nervous system. The rate can be modulated by the rest of the autonomic nervous system.

The coordinated contractions of these layers is called peristalsis and propels the food through the tract. Food in the GI tract is called a bolus ball of food from the mouth down to the stomach.

After the stomach, the food is partially digested and semi-liquid, and is referred to as chyme. In the large intestine the remaining semi-solid substance is referred to as faeces. The outermost layer of the gastrointestinal tract consists of several layers of connective tissue.

Intraperitoneal parts of the GI tract are covered with serosa. These include most of the stomach , first part of the duodenum , all of the small intestine , caecum and appendix , transverse colon , sigmoid colon and rectum. In these sections of the gut there is clear boundary between the gut and the surrounding tissue. These parts of the tract have a mesentery. Retroperitoneal parts are covered with adventitia.

They blend into the surrounding tissue and are fixed in position. For example, the retroperitoneal section of the duodenum usually passes through the transpyloric plane. These include the esophagus , pylorus of the stomach, distal duodenum , ascending colon , descending colon and anal canal. In addition, the oral cavity has adventitia. Specific proteins expressed in the stomach and duodenum involved in defence include mucin proteins, such as mucin 6 and intelectin Finally, transit through the colon takes 12 to 50 hours with wide variation between individuals.

The gastrointestinal tract forms an important part of the immune system. There are additional factors contributing to protection from pathogen invasion. For example, low pH ranging from 1 to 4 of the stomach is fatal for many microorganisms that enter it. Beneficial bacteria also can contribute to the homeostasis of the gastrointestinal immune system. For example Clostridia , one of the most predominant bacterial groups in the GI tract, play an important role in influencing the dynamics of the gut's immune system.

This is due to the production of short-chain fatty acids during the fermentation of plant-derived nutrients such as butyrate and propionate. Basically, the butyrate induces the differentiation of Treg cells by enhancing histone H3 acetylation in the promoter and conserved non-coding sequence regions of the FOXP3 locus, thus regulating the T cells , resulting in the reduction of the inflammatory response and allergies.

The large intestine hosts several kinds of bacteria that can deal with molecules that the human body cannot otherwise break down. These bacteria also account for the production of gases at host-pathogen interface , inside our intestine this gas is released as flatulence when eliminated through the anus. However the large intestine is mainly concerned with the absorption of water from digested material which is regulated by the hypothalamus and the re absorption of sodium , as well as any nutrients that may have escaped primary digestion in the ileum.

Health-enhancing intestinal bacteria of the gut flora serve to prevent the overgrowth of potentially harmful bacteria in the gut.

These two types of bacteria compete for space and "food," as there are limited resources within the intestinal tract. Enzymes such as CYP3A4 , along with the antiporter activities, are also instrumental in the intestine's role of drug metabolism in the detoxification of antigens and xenobiotics. There are many diseases and conditions that can affect the gastrointestinal system, including infections , inflammation and cancer.

Various pathogens can cause gastroenteritis an inflammation of the stomach and small intestine. These can include those organisms that cause foodborne illnesses.

Gastroenteritis is the most common disease of the GI tract. Diverticular disease is a condition that is very common in older people in industrialized countries. It usually affects the large intestine but has been known to affect the small intestine as well.

Diverticulosis occurs when pouches form on the intestinal wall. Once the pouches become inflamed it is known as diverticulitis. Inflammatory bowel disease is an inflammatory condition affecting the bowel walls, and includes the subtypes Crohn's disease and ulcerative colitis.

While Crohn's can affect the entire gastrointestinal tract, ulcerative colitis is limited to the large intestine. Crohn's disease is widely regarded as an autoimmune disease. Although ulcerative colitis is often treated as though it were an autoimmune disease, there is no consensus that it actually is such. Functional gastrointestinal disorders the most common of which is irritable bowel syndrome. Functional constipation and chronic functional abdominal pain are other functional disorders of the intestine that have physiological causes, but do not have identifiable structural, chemical, or infectious pathologies.

Gastrointestinal surgery can often be performed in the outpatient setting. In the United States in , operations on the digestive system accounted for 3 of the 25 most common ambulatory surgery procedures and constituted 9.

Various methods of imaging the gastrointestinal tract include the upper and lower gastrointestinal series:. Animal intestines have multiple uses. From each species of livestock that is a source of milk , a corresponding rennet is obtained from the intestines of milk-fed calves.

Pig and calf intestines are eaten, and pig intestines are used as sausage casings. Calf intestines supply calf-intestinal alkaline phosphatase CIP , and are used to make goldbeater's skin.

Many birds and other animals have a specialised stomach in the digestive tract called a gizzard used for grinding up food. Another feature not found in the human but found in a range of other animals is the crop. In birds this is found as a pouch alongside the esophagus. Other animals including amphibians , birds , reptiles , and egg-laying mammals have a major difference in their GI tract in that it ends in a cloaca and not an anus.

From Wikipedia, the free encyclopedia. Redirected from Human gastrointestinal tract. For other uses, see Guts disambiguation. Esophagus , Stomach , and duodenum. Development of the digestive system. Duct of gland outside tract 7: Gland in mucosa 8: Glands in submucosa Meissner's submucosal plexus Areolar connective tissue Auerbach's myenteric plexus Oral mucosa and Gastric mucosa.

Serous membrane and Adventitia. This section discusses related diseases, medical associations with the gastrointestinal tract, and use in surgery. Gastrointestinal disease and Gastroenterology. Ruminant and Methanogens in digestive tract of ruminants. This article uses anatomical terminology; for an overview, see Anatomical terminology.

Invertebrate Zoology 7 ed. Surgical and Radiologic Anatomy. Factor in achieving total enteroscopy? H; Fava, F; Hermes, G. M; Hold, G; Quraishi, M. G; Hart, A A new clinical frontier". The Neglected Endocrine Organ". Introduction to Behavioral Endocrinology. Retrieved 2 September Oxford textbook of medicine:

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